Compound K improves skin barrier function by increasing SPINK5 expression
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چکیده
منابع مشابه
Trimetazidine improves right ventricular function by increasing miR-21 expression.
Trimetazidine (TMZ) improves left ventricular (LV) function and alleviates angina. TMZ is a metabolism-related drug, but its molecular actions and non-metabolic effects have not yet been elucidated. In this study, we investigated whether TMZ improves right ventricular (RV) function and decreases apoptosis in RV myocardial cells (RVMCs) by regulating miRNA-21 (miR-21) expression in vitro and in ...
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BACKGROUND Kinetin is a plant hormone that regulates growth and differentiation. Keratinocytes, the basic building blocks of the epidermis, function in maintaining the skin barrier. OBJECTIVE We examined whether kinetin induces skin barrier functions in vitro and in vivo. METHODS To evaluate the efficacy of kinetin at the cellular level, expression of keratinocyte differentiation markers wa...
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OBJECTIVES/HYPOTHESIS Chronic rhinosinusitis (CRS) is a multifactorial disease that probably arises as a result of genetic diversity and environmental factors. SPINK5 is a serine protease inhibitor, which is supposed to be an important regulator of epithelial barrier maintenance. The role of SPINK5 polymorphisms and expression in CRS, especially in individuals with aspirin intolerance, is uncle...
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ژورنال
عنوان ژورنال: Journal of Ginseng Research
سال: 2020
ISSN: 1226-8453
DOI: 10.1016/j.jgr.2019.11.006